Pinealon

Description

Properties

CAS Number	175175-23-2
Molar Mass	418.40 g/mol
Chemical Formula	C15H26N6O8
Synonyms	Glu-Asp-Arg,Glutamyl-aspartyl-arginine, CHEBI:156374, L-Glutamyl-L-aspartyl-L-arginine
Shelf Life	Powder form: 24 months Reconstituted: 2 to 3 weeks (Refrigerated storage of 2–8°C)

Product Overview of Pinealon Peptide

Pinealon (Glu-Asp-Arg) refers to a short synthetic tripeptide. Although it is a man-made compound, it has attracted growing interest in various fields such as:

• Neurobiology
• Aging
• Stress response

Structurally, Pinealon consists of three amino acids (glutamic acid, aspartic acid, and arginine), accounting for its small size. This enables the research compound to potentially cross cellular and nuclear membranes.

Unlike many peptides that act via cell-surface receptors, Pinealon is hypothesized to penetrate the nucleus and directly influence gene expression.[1]

Some preclinical research suggests that Pinealon peptide may regulate innate pathways related to oxidative stress, apoptosis, cognitive function, and circadian rhythm. [2]

Even though the exact mechanism of action is being investigated, studies have reported that Pinealon may lead to the following effects:

• Reduce markers of oxidative damage
• Potentially improve cognitive outcomes
• Support neuronal survival under stress conditions

All of the actions mentioned above were observed outcomes in animal models. Pinealon is not FDA-approved for human consumption. BC9 strictly sells its Pinealon vial for laboratory research purposes only.

Why Choose BC9 to Buy Pinealon Peptide Online

At BC9, our team is renowned for empowering breakthrough-level research studies. This is achieved by providing laboratory-grade Pinealon peptide for sale. The studies that our Pinealon vial supports are related to neuroscience, aging, and cellular health.

When you choose BC9 to buy Pinealon peptide online, you receive:

• High-quality Pinealon peptide that is manufactured under strict quality standards
• A free reconstitution kit to help your study move forward
• Transparent product testing
• Discreet shipping; Free shipping applies to US orders above $150
• Reliable and knowledgeable 24/7 customer support

Regardless of your research setup, in vitro work, or preclinical animal studies, BC9 can ensure you have access to a dependable and research-ready peptide compound.

Pinealon Peptide: Potential Research Applications

Neuroprotection and Oxidative Stress

Research indicates that Pinealon may act as a neuroprotective agent as it mitigates oxidative stress. The latter is a known key driver of neuronal damage and aging. [4]

Pinealon administration was also linked to reduced reactive oxygen species (ROS) production. Plus, this research compound could improve antioxidant enzyme activity. These two actions may help preserve neuronal structure and function. [3]

Circadian Rhythm and Pineal Gland Regulation

Some studies have concluded that Pinealon may influence circadian regulation. The idea is that this compound has the potential to influence certain pathways connected to the pineal gland. The latter governs the body’s sleep-wake cycle and melatonin production. [4]

One study in Russia examined how occupational hazards and work schedules can influence neurobehavioral status. According to the findings, there were higher rates of instability and disadaptation when research subjects were exposed to prolonged stress. Research further indicated that experimental peptides, such as Pinealon, supported adapted potential and reduced associated risk factors. [5]

However, this was done within a controlled experimental setting. More studies are required to confirm Pinealon’s effect on the human circadian rhythm.

Cognitive Function and Learning

Animal experiments have shown promising results for Pinealon. These were observed to support memory formation and learning capacity.

One study utilized prenatal rat models that were exposed to stress. The researchers noted that rodent offspring receiving Pinealon demonstrated better spatial learning. They were also able to demonstrate improved motor coordination and enhanced memory retention. [3]

However, it is important to note that these results are preliminary. Pinealon has not been approved for human consumption. More studies are needed to verify its safety among humans.

Anti-Apoptotic and Cellular Survival

Pinealon has been observed to reduce the activity of caspase-3. It is a central enzyme in programmed cell death. [6] [7]

The research compound demonstrated the ability to dampen pathways for caspase-3 to operate. Through such action, Pinealon may help extend the survival of neurons and other vulnerable cell types when placed in stressful situations.

Because Pinealon has a potential cryoprotective property, it can become a promising candidate for research into age-related cellular degeneration.

IMPORTANT:

The possible effects mentioned above have been observed only within controlled experimental and preclinical settings. These findings should not be interpreted as evidence of clinical efficacy or safety among humans. Pinealon has not been approved for medical use. More large-scale studies are required to evaluate its safety in humans.

Frequently Asked Questions

What should you consider before you buy Pinealon peptide online?

As you decide to purchase Pinealon peptide for research, several factors have to be considered. First, ensure that the supplier provides high-purity material, clear documentation, and reliable third-party testing. The latter can be verified by an updated certificate of analysis (COA).

You should also confirm that the peptide is intended solely for laboratory use. A clear labeling of such an instruction should suffice.

Can Pinealon be considered a nootropic chemical?

Although not entirely a nootropic, Pinealon was observed to demonstrate certain cognitive-enhancing properties, but these are all confined to laboratory research subjects. Still, in preclinical and experimental studies, Pinealon has a potential role in cellular adaptation, oxidative stress, and neurobiology.

How is Pinealon studied in research settings?

In experimental studies, Pinealon is normally investigated in vitro or in animal models. Some of the goals include evaluating its effects on oxidative stress, cellular adaptation, cognitive function, and neuronal survival.

Does Pinealon lead to side effects?

The safety profile of Pinealon has not been established in humans. Reported findings are limited to preclinical animal models. Despite this, it is essential to remember that Pinealon is not FDA-approved for human consumption.

Why is BC9 a trusted supplier if you aim to purchase Pinealon online?

BC9 provides high-purity Pinealon peptide for sale, complete with third-party quality verification. Each vial even comes with a free reconstitution kit. Moreover, our company is recognized for transparent practices, customer support, and fast and discreet delivery.

References:

1. Fedoreyeva, L. I., Kireev, I. I., Khavinson, V. K., & Vanyushin, B. F. (2011). Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribooligonucleotides and DNA. Biochemistry (Moscow), 76(11), 1210–1219. https://doi.org/10.1134/s0006297911110022 
2. Khavinson, V., Ribakova, Y., Kulebiakin, K., Vladychenskaya, E., Kozina, L., Arutjunyan, A., & Boldyrev, A. (2011b). Pinealon increases cell viability by suppressing free radical levels and activating proliferative processes. Rejuvenation Research, 14(5), 535–541. https://doi.org/10.1089/rej.2011.1172
3. Arutjunyan, A., Kozina, L., Stvolinskiy, S., Bulygina, Y., Mashkina, A., & Khavinson, V. (2012, April 6). Pinealon protects the rat offspring from prenatal hyperhomocysteinemia. https://pmc.ncbi.nlm.nih.gov/articles/PMC3342713/
4. Goncharova, N., Vengerin, A., Khavinson, V., & Lapin, B. (2004). Pineal peptides restore the age-related disturbances in hormonal functions of the pineal gland and the pancreas. Experimental Gerontology, 40(1–2), 51–57. https://doi.org/10.1016/j.exger.2004.10.004 
5. [The peptide correction of neurotic disorders among professional truck drivers]. (2012). PubMed. https://pubmed.ncbi.nlm.nih.gov/23734521/
6. Robertson, G. S., Crocker, S. J., Nicholson, D. W., & Schulz, J. B. (2000). Neuroprotection by the inhibition of apoptosis. Brain Pathology, 10(2), 283–292. https://doi.org/10.1111/j.1750-3639.2000.tb00262.x
7. Yayuan, Y., Ling, H., Qunli, Y., Yongfang, G., & Hongmei, S. (2021). Effects of caspase activity of yak meat and the internal environment changing during aging. Journal of Food Science and Technology, 59(4), 1362–1371. https://doi.org/10.1007/s13197-021-05145-x