NSI 189 Phosphate Powder
Property | Value |
---|---|
CAS Number | 1270138-40-3 |
Molar Mass | 366.509 g·mol⁻¹ |
Chemical Formula | C₂₂H₃₀N₄O |
IUPAC Name | (4-Benzylpiperazin-1-yl)-[2-(3-methylbutylamino)pyridin-3-yl]methanone |
Introduction
NSI 189 Phosphate is a research product designed for scientific exploration and not intended for human consumption. This compound is valuable for researchers studying its unique properties and potential benefits.
Key Characteristics
NSI 189 Phosphate is a derivative of benzylpiperazine and has gained scientific interest due to its potential neuro regenerative properties. Recognized for its role in neurogenesis, it is a key area of neuroscience research.
Research Applications
NSI 189 Phosphate is widely studied for its potential therapeutic applications, particularly in major depressive disorder (MDD), ischemic stroke, and diabetic neuropathy.
Research Benefits
NSI 189 Phosphate and Major Depressive Disorder (MDD)
Studies suggest that NSI 189 Phosphate may help in treating major depressive disorder. Research aims to understand its mechanism of action and therapeutic potential for depressive disorders.
NSI 189 Phosphate and Ischemic Stroke
Preliminary research indicates that NSI 189 Phosphate may have neuroprotective effects, particularly in ischemic stroke. Studies on its effects on neuronal survival and recovery explore its potential in stroke treatment.
NSI 189 Phosphate and Diabetic Neuropathy
Research suggests that NSI 189 Phosphate may have implications for diabetic neuropathy, potentially influencing nerve function and regeneration. Studies examine its effects on diabetic neuropathy and nerve regeneration.
Disclaimer
This content is for educational purposes only and should not be considered medical advice. The materials referenced herein are strictly intended for laboratory and research use.
An Institutional Review Board (IRB) must approve all clinical research. Preclinical research involving animals must comply with Institutional Animal Care and Use Committee (IACUC) guidelines and adhere to the Animal Welfare Act (AWA).
Our content provides research-oriented insights but is not a substitute for independent verification from credible sources before making purchasing decisions.
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IMPORTANT NOTICE:
All products listed on our platform are EXCLUSIVELY FOR LABORATORY AND RESEARCH APPLICATIONS and are not intended for human or veterinary use.
References
- Fava M, Johe K, Ereshefsky L, Gertsik LG, English BA, Bilello JA, Thurmond LM, Johnstone J, Dickerson BC, Makris N, Hoeppner BB, Flynn M, Mischoulon D, Kinrys G, Freeman MP. (2016). A Phase 1B, randomized, double-blind, placebo-controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients. Molecular Psychiatry, 21(10), 1372-1380. [Read More]
- Tajiri, N., Quach, D. M., Kaneko, Y., et al. (2017). NSI-189, a small molecule with neurogenic properties, exerts behavioral and neurostructural benefits in stroke rats. Journal of Cellular Physiology, 232, 2731–2740. [Read More]
- Jolivalt, C. G., Marquez, A., Quach, D., et al. (2019). Amelioration of Both Central and Peripheral Neuropathy in Mouse Models of Type 1 and Type 2 Diabetes by the Neurogenic Molecule NSI-189. Diabetes, 68(11), 2143-2154. [Read More]
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