Theacrine Tablets

Description

Properties

CAS Number	2309-49-1
Molar Mass	224.22 g/mol
Chemical Formula	C9H12N4O3
Synonyms	Tetramethyluric acid, 2309-49-1, 1,3,7,9-Tetramethyluric acid, Temurine
Shelf Life	2 years when placed in a cool, dry place

Product Overview of Theacrine Tablets

Theacrine is a naturally occurring purine alkaloid. This compound is primarily found in the leaves of Camellia assamica var. Kucha. 

Structurally similar to caffeine, Theacrine has drawn interest from researchers due to its unique interaction with the adenosine and dopamine systems. The mentioned pathways are associated with processes such as energy levels, concentration, mood, and motivation.

Unlike caffeine, Theacrine has been investigated for its potential to deliver longer-lasting effects without rapid tolerance buildup. Early research even suggests that this chemical may avoid specific adverse effects. These are typically linked to stimulants. As such, Theacrine becomes a valuable candidate for continued investigation in fields such as neuromodulation, metabolism, and compound solutions.

Laboratory and preclinical research have explored several possible applications of Theacrine, such as:

• Energy and focus mechanisms when placed side-by-side to caffeine on endurance models
• Neurological pathways tied to mood, motivation, and dopamine signaling
• Effects on lipid metabolism, including possible impacts on cholesterol
• Investigations into adenosine regulation, inflammation, and pain responses

BC9’s Theacrine tablets provide this compound in a standardized format with precise 150 mg of Theacrine per unit. This ensures consistent dosage and reproducibility across research settings.

Why Choose BC9 to Buy Theacrine Tablets Online

When it comes to Theacrine buy options, BC9 offers reliable access to high-quality Theacrine for sale, suitable for laboratory and academic research purposes. Our Theacrine is derived from Camellia assamica var. Kucha. The latter refers to a natural source containing this specific purine alkaloid.

Researchers often compare Theacrine to compounds similar to caffeine. This explains why Theacrine has been studied for its potential influence on adenosine signaling.

What sets BC9’s Theacrine apart from other brands is that we emphasize consistent stock, accurate quantity, and uncompromising control over ingredients.

Here are other features that make BC9 your best go-to supplier of research products, Theacrine included:

• 100% Customer Satisfaction: Our products consistently receive high reviews from our clients.
• Comprehensive Catalogue: Aside from Theacrine, we also offer other similar research compounds. Each is categorized according to its potential research application.
• Transparent Documentation: When you choose to buy a product, expect to receive full details on sourcing, ingredients, and specifications.
• Research-Grade Ingredients: We sell research items that contain no unnecessary additives or unwanted other ingredients.
• Quality Assurance: Every batch undergoes rigorous testing to meet strict consistency and reproducibility standards.
• 24/7 Customer Support: Our BC9 team is here for you. We can assist you with orders and inquiries related to our products.
• Free Shipping in the US: Enjoy fast, discreet, and free delivery of your research products. This applies to orders above $150.
• Multiple Payment Options: Explore our wide variety of payment options. Each is designed to support your research.

Theacrine Tablets: Potential Research Applications

Energy, Focus, and Motivation

Preliminary research indicates that Theacrine may influence both the adenosine and dopamine systems. These are two pathways central to stimulation and alertness. In small-scale studies, subjects reported heightened energy levels, greater concentration, and increased willingness to engage in activity following controlled Theacrine exposure.[1]

Animal experiments further support these findings, with Theacrine significantly enhancing locomotor activity among rats. This effect suggests a potential mechanism for sustained energy and focus without the rapid tolerance often observed with compounds similar to caffeine.[2]

Mood and Reward Pathways

Theacrine’s interaction with dopamine receptors (e.g., DRD1 and DRD2) has been documented in animal studies. Theacrine has been shown to elevate signaling in brain regions linked to mood, pleasure, and motivation. [3]

Some investigations combined Theacrine with caffeine, reporting favorable outcomes. These refer to reduced lethargy and improved subjective measures of alertness.

Among mouse models, Theacrine demonstrated antidepressant-like activity. This aligns with the compound’s proposed impact on the brain’s reward circuitry. [4]

Cholesterol and Metabolic Factors

One controlled study stated that high-dose Theacrine may modestly reduce specific biomarkers. These point to LDL and total cholesterol levels. This action could be attributed to its specific polyphenols, which are known to influence lipid metabolism. [7]

Sleep and Adenosine Regulation

This potential is based on some rodent studies. It was shown that low doses of Theacrine led to reduced wake time, enhanced sleep duration, and even lessened caffeine-induced insomnia. Such effects may be due to higher adenosine concentrations in the hippocampus. As such, this suggests that Theacrine may help regulate sleep through neuromodulatory models. [5]

Inflammation and Pain Models

Theacrine has also been shown to lessen inflammation in mouse research models. The compound’s potency may be comparable to certain anti-inflammatory agents, though it could offer a generally weaker effect. [6]

Interestingly, the study also concludes that Theacrine’s pain-relieving effects were dose-dependent. On the other hand, caffeine showed little to no impact under similar conditions.

Theacrine vs Caffeine

Caffeine is well-documented to cause tolerance, withdrawal, and adverse effects. These could be anxiety and insomnia. [8] On the other hand, Theacrine appears non-habituating over extended daily use. This effect is, however, limited to early clinical studies. [9]

Some animal studies suggest that Theacrine may avoid the blood pressure spikes and anxiety commonly associated with caffeine.

Frequently Asked Questions

What is Theacrine?

Theacrine is a naturally occurring purine alkaloid found in Camellia assamica var. kucha. It has structural similarities to and functions similarly to caffeine.

What makes BC9 a reliable supplier of Theacrine for sale online?

BC9 maintains consistent stock, precise mg of Theacrine per unit, and strict quality standards.  We also provide Certificates of Analysis for all of our products to guarantee purity and effectiveness.

How should Theacrine be categorized?

Theacrine is not classified as a therapeutic drug or dietary supplement. It is a research-only compound provided for academic and laboratory use.

Is Theacrine better than caffeine?

Theacrine is structurally similar to caffeine. However, research suggests that it may not build tolerance as quickly and could have fewer adverse effects. On the other hand, caffeine is far more extensively studied, while Theacrine remains an emerging area of research.

Does Theacrine come with side effects?

Theacrine may produce fewer adverse effects. These may include tolerance or sleep disruption. However, studies remain limited, and more data are needed to fully understand its safety profile.

References:

1. Ziegenfuss, T. N., Habowski, S. M., Sandrock, J. E., Kedia, A. W., Kerksick, C. M., & Lopez, H. L. (2017). A Two-Part Approach to Examine the Effects of Theacrine (TeaCrine®) Supplementation on Oxygen Consumption, Hemodynamic Responses, and Subjective Measures of Cognitive and Psychometric Parameters. Journal of Dietary Supplements, 14(1), 9–24. https://doi.org/10.1080/19390211.2016.1178678
2. Kuhman, D., Joyner, K., & Bloomer, R. (2015). Cognitive Performance and Mood Following Ingestion of a Theacrine-Containing Dietary Supplement, Caffeine, or Placebo by Young Men and Women. Nutrients, 7(11), 9618–9632. https://doi.org/10.3390/nu7115484 
3. Feduccia, A. A., Wang, Y., Simms, J. A., Yi, H. Y., Li, R., Bjeldanes, L., Ye, C., & Bartlett, S. E. (2012). Locomotor activation by theacrine, a purine alkaloid structurally similar to caffeine: involvement of adenosine and dopamine receptors. Pharmacology, Biochemistry, and Behavior, 102(2), 241–248. https://doi.org/10.1016/j.pbb.2012.04.014 
4. Sheng, Y.-Y., Xiang, J., Wang, Z.-S., Jin, J., Wang, Y.-Q., Li, Q.-S., Li, D., Fang, Z.-T., Lu, J.-L., Ye, J.-H., Liang, Y.-R., & Zheng, X.-Q. (2020). Theacrine from Camellia kucha and Its Health Beneficial Effects. Frontiers in Nutrition, 7, 596823. https://doi.org/10.3389/fnut.2020.596823  
5. Qiao, H., Ye, X., Bai, X., He, J., Li, T., Zhang, J., Zhang, W., & Xu, J. (2017). Theacrine: A purine alkaloid from Camellia assamica var. kucha with a hypnotic property via the adenosine system. Neuroscience Letters, 659, 48–53. https://doi.org/10.1016/j.neulet.2017.08.063 
6. Wang, Y., Yang, X., Zheng, X., Li, J., Ye, C., & Song, X. (2010). Theacrine, a purine alkaloid with anti-inflammatory and analgesic activities. Fitoterapia, 81(6), 627–631. https://doi.org/10.1016/j.fitote.2010.03.008
7. Taylor, L., Mumford, P., Roberts, M., Hayward, S., Mullins, J., Urbina, S., & Wilborn, C. (2016). Safety of TeaCrine®, a non-habituating, naturally occurring purine alkaloid, over eight weeks of continuous use. Journal of the International Society of Sports Nutrition, 13, 2. https://doi.org/10.1186/s12970-016-0113-3 
8. Sajadi-Ernazarova, K. R., & Hamilton, R. J. (2023, August 8). Caffeine Withdrawal. National Library of Medicine; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK430790/ 
9. Bello, M. L., Walker, A. J., McFadden, B. A., Sanders, D. J., & Arent, S. M. (2019). The effects of TeaCrine® and caffeine on endurance and cognitive performance during a simulated match in high-level soccer players. Journal of the International Society of Sports Nutrition, 16(1). https://doi.org/10.1186/s12970-019-0287-6   
10. Cintineo, H. P., Bello, M. L., Chandler, A. J., Cardaci, T. D., McFadden, B. A., & Arent, S. M. (2022). Effects of caffeine, methylliberine, and theacrine on vigilance, marksmanship, and hemodynamic responses in tactical personnel: a double-blind, randomized, placebo-controlled trial. Journal of the International Society of Sports Nutrition, 19(1), 543–564. https://doi.org/10.1080/15502783.2022.2113339