Apigenin Powder

Description

Product Information

CAS Number	520-36-5
Molar Mass	270.24 g/mol
Chemical Formula	C15H10O5
Synonyms	520-36-5 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one Versulin Apigenol
Shelf Life	24 months when stored within recommended conditions

Product Overview

BC9 sells one of the purest apigenin powders for research. It is a naturally occurring flavonoid obtained from plant sources. These may refer to chamomile, parsley, and citrus. 

It is widely used in scientific environments. The reason behind this is that it possesses diverse biochemical properties. These include interactions with neurotransmitter systems, antioxidant mechanisms, and cellular signaling pathways.

Our research-grade apigenin powder is offered exclusively for laboratory use. It is suited only for analytical work and controlled experimental applications. Thus, BC9’s apigenin powder is not approved for human consumption.

Why Choose BC9 to Buy Apigenin Powder Online?

High Purity & Verified Identity

Every batch of our products undergoes rigorous testing. This involves HPLC testing, microbial screening, and identity confirmation. By doing so, we can ensure consistent research performance.

Stable, Fine Powder for Easy Handling

This research compound is processed for a uniform particle size. This helps researchers to achieve accurate measurements and reproducible results.

Research-Only Use (ROU)

Our apigenin powder is formulated for research purposes alone. It is intended exclusively for scientific, laboratory, and in vitro applications.

Mechanism of Action

Apigenin is known to interact with several cellular targets:

• GABA-A Modulation: Apigenin has demonstrated affinity for GABA-A receptor subunits. In turn, it becomes useful in neurochemical and receptor-binding research. [1]
• Antioxidant Activity: The molecule may act as a potent scavenger of reactive oxygen species. Thus, apigenin can help studies requiring biochemical assays. [2]
• Anti-inflammatory Pathways: The apigenin compound has been shown to modulate NF-κB activity. It may also reduce pro-inflammatory cytokine expression in cell models. [3]
• Enzyme Interactions: Based on some scientific literature, apigenin is believed to influence key enzymes. These may include aromatase. As such, the chemical compound is valuable in hormonal and metabolic research fields. [4]
• Neuroprotective Mechanisms: Laboratory models suggest that apigenin may support neuronal cell integrity. This effect may have been observed under oxidative or inflammatory stress. [5]

The mentioned mechanisms allow scientists to explore apigenin’s effects across various fields. Examples of these are molecular biology, biochemistry, and neuropharmacology research.

Potential Research Applications

IMPORTANT: All information below refers to findings from laboratory, animal, or in vitro models. They are provided for research and educational purposes alone. These should not be construed as medical advice or therapeutic promotion. BC9 apigenin is not intended for human consumption.

Potential Calming Pathway Modulation

Studies show that apigenin can bind to GABA-A receptors in neuronal models. This potential provides a framework for research into stress-related biochemical pathways.

Sleep-Related Mechanisms

Chamomile extracts are known for being rich in apigenin. As such, they have been investigated for their impact on sleep parameters in controlled environments.

Antioxidant Activity

Apigenin was observed to display a strong radical-scavenging capacity. This explains why scientists view it as a valuable compound for studying oxidative stress and cellular aging.

Anti-Inflammatory Signaling

Cell-based studies involving apigenin reductions in IL-6 and TNF-α. Thus, the research chemical may support research related to inflammatory cascades and immune modulation.

Hormonal Pathway Investigation

Apigenin has the potential to inhibit the aromatase enzyme in laboratory assays. The compound becomes a candidate for exploring hormone-related biochemical processes.

Neuroprotection & Cognitive Pathways

In neuronal models, apigenin may reduce oxidative and inflammatory stress. The potential effect can help researchers observe neurodegeneration, brain aging, and cellular resilience.

Vascular & Blood Pressure Research

Animal studies indicate that apigenin may promote vasodilation. This creates opportunities for cardiovascular research focused on blood vessel relaxation.

Frequently Asked Questions

Is BC9 apigenin powder safe for human consumption?

No. This product is strictly limited to laboratory and research use. BC9 does not sell it as a food, supplement, or therapeutic compound.

How should the compound be stored?

Store in a cool, dry, and dark environment. Reseal tightly after using to maintain stability.

What purity level does BC9’s apigenin powder offer?

Each batch is typically ≥98% purity (HPLC verified). Certificates of Analysis (COAs) is available upon request.

What research fields commonly use apigenin?

Neuroscience, antioxidant research, inflammation studies, enzymatic pathway analysis, cellular biology, and metabolic research.

References

1. Marder, M. (2012). Flavonoids as GABAA receptor ligands: the whole story? Journal of Experimental Pharmacology, 4, 9. https://doi.org/10.2147/jep.s23105
2. Alghamdi, A., Almuqbil, M., Alrofaidi, M. A., Burzangi, A. S., Alshamrani, A. A., Alzahrani, A. R., Kamal, M., Imran, M., Alshehri, S., Mannasaheb, B. A., Alomar, N. F., & Asdaq, S. M. B. (2022). Potential antioxidant activity of apigenin in the obviating Stress-Mediated depressive symptoms of experimental mice. Molecules, 27(24), 9055. https://doi.org/10.3390/molecules27249055
3. Charrière, K., Schneider, V., Perrignon-Sommet, M., Lizard, G., Benani, A., Jacquin-Piques, A., & Vejux, A. (2024). Exploring the role of apigenin in neuroinflammation: Insights and implications. International Journal of Molecular Sciences, 25(9), 5041. https://doi.org/10.3390/ijms25095041
4. Long, X., Fan, M., Bigsby, R. M., & Nephew, K. P. (2008). Apigenin inhibits antiestrogen-resistant breast cancer cell growth through estrogen receptor-α-dependent and estrogen receptor-α-independent mechanisms. Molecular Cancer Therapeutics, 7(7), 2096–2108. https://doi.org/10.1158/1535-7163.mct-07-2350
5. Dourado, N. S., Souza, C. D. S., De Almeida, M. M. A., Da Silva, A. B., Santos, B. L. D., Silva, V. D. A., De Assis, A. M., Da Silva, J. S., Souza, D. O., De Fatima Dias Costa, M., Butt, A. M., & Costa, S. L. (2020). Neuroimmunomodulatory and Neuroprotective Effects of the Flavonoid Apigenin in in vitro Models of Neuroinflammation Associated With Alzheimer’s Disease. Frontiers in Aging Neuroscience, 12, 119. https://doi.org/10.3389/fnagi.2020.00119