Description
| Myo-Inositol Trispyrophosphate (ITPP) | |
| CAS Number | 623552-11-4 |
| Molar Mass | 605.984 g/mol |
| Chemical Formula | C17H18F3N3O3 |
| IUPAC Name | [[(2R,3R,4R,5R)-6-(dihydrogen phosphate)-3,4,5-trihydroxyoxan-2-yl]methyl] bis(dihydrogen diphosphate) |
Introduction
ITPP, or myo-Inositol Trispyrophosphate, is a highly phosphorylated derivative of myo-inositol that has gained attention in research for its ability to modify oxygen release from hemoglobin. It is primarily studied in laboratory and animal models for its potential effects on metabolic efficiency and cardiovascular performance.
Key Characteristics
Molecularly modified to enhance oxygen unloading from red blood cells, ITPP is highly soluble and stable in aqueous environments and is often utilized in capsule, tablet, or powder form for experimental protocols.
Research Applications
Enhanced Endurance in Models
ITPP has been used in preclinical studies to investigate improvements in exercise capacity and endurance metrics in animal models.
Increased Stamina Potential
Studies suggest ITPP can support sustained physical activity by improving oxygen availability at the tissue level.
Accelerated Recovery Studies
Research explores its role in promoting faster recovery from metabolic stress or high-intensity exertion in controlled experimental settings.
Summary
ITPP serves as a valuable compound in research exploring oxygen transport, endurance enhancement, and recovery mechanisms. Its application in experimental studies contributes to a better understanding of metabolic and cardiovascular dynamics under controlled conditions.
Disclaimer
This content is presented exclusively for educational purposes and should not be construed as medical advice. THE MATERIALS REFERENCED HEREIN ARE EXCLUSIVELY INTENDED FOR LABORATORY AND RESEARCH USE.
Any clinical research initiatives must be conducted under the guidance of the relevant Institutional Review Board (IRB). Similarly, preclinical research involving animals must comply with the directives of the Institutional Animal Care and Use Committee (IACUC), adhering to the standards delineated by the Animal Welfare Act (AWA).
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References
Görgens, C. (2014). Screening and confirmation of myo‐inositol trispyrophosphate in human urine by ion chromatography coupled to high‐resolution mass spectrometry. Drug Testing and Analysis, 6(10), 1000–1006 [Read More].
Wong, A. S. Y., Ho, E. N. M., & Wan, T. S. M. (2012). Detection of myo‐inositol trispyrophosphate in equine urine and plasma by hydrophilic interaction chromatography‐tandem mass spectrometry. Drug Testing and Analysis, 4(5), 355–361.[Read More].
Görgens, C., Guddat, S., Schänzer, W., & Thevis, M. (2014). Screening and confirmation of myo-inositol trispyrophosphate (ITPP) in human urine by hydrophilic interaction liquid chromatography high resolution/high-accuracy mass spectrometry for doping control purposes. Drug Testing and Analysis, 6(11–12), 1102–1107.[Read More].





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